4-AcO-DMT Uses, Health Risks, Legality and Effects
4-AcO-DMT is a synthetically produced psychoactive drug used as an alternative to psilocybin, a naturally occurring psychedelic prodrug compound produced by more than 200 species of mushrooms which is used for pharmacological studies. The drug 4-AcO-DMT is also an acetylated form of the psilocybin mushroom alkaloid psilocin which was originally patented by Sandoz Ltd in 1963. The psilocybin-like effect produced by 4-AcO-DMT has been linked to the structural similarity of the latter to the former. As a result of its ability elicit traditional entheogenic (spirituality-enhancing agent) effects
despite having a purely synthetic origin, this hitherto unknown drug has gained worldwide prominence and has become of one of the a grey area research chemical since appearing online. 4-AcO-DMT is also a lower homolog of 4-AcO-MET, 4-AcO-DET, 4-AcO-MiPT and 4-AcO-DiPT, the other names of 4-AcO-DMT include O-Acetylpsilocin, Psilacetin and 4-acetoxy-DMT.
Effects, Uses and Side Effected of 4-AcO-DMT
The effects of 4-AcO-DMT are often compared to those of psychedelic tryptamines like psilocybin mushrooms and DMT. In general, 4-AcO-DMT is used as an alternative to psilocybin for pharmacological studies as both drugs are thought to act as prodrugs for psilocin (4-HO-DMT), the primary active component of psilocybin mushrooms and typically taken orally.
The administration of 4-AcO-DMT in whatever form produces a wide range of subjective effects such as:
- Feelings of disorientation
- Lethargy, giddiness, euphoria
- Joy and depression.
- Feeling of anxiety or paranoia.
- hallucinatory effects.
- Closed-eye hallucinations may also occur with 4-AcO-DMT use
- Open-eye visual hallucinations are common with 4-AcO-DMT use
- Synesthesia, such as tactile sensations when viewing colors.
- Sedation often accompanied by compulsive yawning.
- Higher doses 4-AcO-DMT can lead to Intensification of affective responses, total immobilization, enhanced ability for introspection, regression to primitive and childlike thinking, activation of vivid memory traces and pronounced emotional undertones
Health Risk of 4-AcO-DMT
The Use of 4-AcO-DMT or its derivatives have a far reaching effects on mental and behavioral health. Most of the effects produced by 4-AcO-DMT and its derivatives undermine the body’s normal functions making affected individuals become extremely anxious, confused, agitated, or disoriented. Accidents, self-injury, or suicide attempts often result from serious cases of acute psychotic episodes related to the use of 4-AcO-DMT and similar drugs. Depression, one of the major side effects of 4-AcO-DMT is the leading cause of disability measured by Years Lived with Disability (YLDs).
Existing research findings has already linked depression to a heightened risk of cardiovascular disease and sudden cardiac death, especially in women. A recently published study in the Canadian Medical Association Journal conducted by researchers from across U.S. and Canadian institutions, including the Eunice Kennedy Shriver National Institute of Child Health and Human Development (of the National Institutes of Health) in Bethesda, MD, and the School of Epidemiology at the University of Ottawa in Ontario, Canada points to major depressive episodes as a significant risk factor of early death for both men and women.
The legal status of 4-AcO-DMT varies from country to country. In the United states, 4-AcO-DMT is an unscheduled drug under the Controlled Substance Act (CSA) because it is considered a research chemical. However, sale, being in possession or buying 4-AcO-DMT for human consumption can be illegal under the Federal Analogue Act, under which any substance “substantially similar” to an illegal substance listed in Schedule I or II is treated like those in schedules. 4-AcO-DMT is illegal in the UK, Brazil, Italy and Sweden.