Euphoria refers to an affective state characterized by feelings of intense pleasure, happiness, contentment, and excitement. Several common recreational drugs exhibit addictive properties due to the reward response they induce in the brain. Some of these drugs directly induce the dopamine response (i.e., reward response), while others engage the opioid receptors (responsible for the management of stress, pain, appetite, emotion, and attachment behaviors.
The brain’s reward system mediates behavioral activities related to acquiring natural rewards. In addition, the reward system is the principal neural system targeted by drugs of abuse. Many contemporary public health issues, including obesity, overpopulation, tobacco use, alcoholism, and other drug-use disorders are strongly linked to reward system function and dysfunction. While a variety of complicated environmental and biological factors converge in determining an individual’s risk of substance abuse and dependence, the final common events leading to an individual’s drug use reside within the brain’s neural circuitry.
What is CBD?
CBD stands for cannabidiol. It is the second most prevalent of the active ingredients of cannabis (marijuana). While CBD is an essential component of medical marijuana, it is derived directly from the hemp plant, which is a cousin of the marijuana plant.
Does CBD Get You High?
While CBD is a component of marijuana (one of hundreds), by itself it does not cause a “high.” According to a report from the World Health Organization, “In humans, CBD exhibits no effects indicative of any abuse or dependence potential…. To date, there is no evidence of public health related problems associated with the use of pure CBD.”
Does vaping CBD get you high?
Although pure CBD does not contain any psychoactive substance to get you high, It can expose and compromise your health.A ccording to the Wall Street Journal, the vaping crisis began in the middle of last year, at a hospital in Wisconsin when doctors realized six healthy, often teenage patients were admitted in a short period of time, presenting with shortness of breath, chest pain, and fatigue, but without any sign of infection. The common denominator was, reportedly, vaping. That signaled alarm bells across the country, launched criminal investigations against vaping device companies, and spurred investigations by medical journals, all leading to what’s currently known about the vaping-related illnesses, which the CDC has now officially dubbed “e-cigarette, or vaping, product use associated lung injury,” or EVALI. As of January this year, the Centers for Disease Control and Prevention (CDC) confirmed 60 deaths in patients with e-cigarette, or vaping, product use associated lung injury (EVALI).
The evidence for cannabidiol health benefits
CBD has been touted for a wide variety of health issues, but the strongest scientific evidence is for its effectiveness in treating some of the cruelest childhood epilepsy syndromes, such as Dravet syndrome and Lennox-Gastaut syndrome (LGS), which typically don’t respond to antiseizure medications. In numerous studies, CBD was able to reduce the number of seizures, and in some cases it was able to stop them altogether. Videos of the effects of CBD on these children and their seizures are readily available on the Internet for viewing, and they are quite striking. Recently the FDA approved the first ever cannabis-derived medicine for these conditions, Epidiolex, which contains CBD. CBD is commonly used to address anxiety, and for patients who suffer through the misery of insomnia, studies suggest that CBD may help with both falling asleep and staying asleep.
CBD may offer an option for treating different types of chronic pain. A study from the European Journal of Pain showed, using an animal model, CBD applied on the skin could help lower pain and inflammation due to arthritis. Another study demonstrated the mechanism by which CBD inhibits inflammatory and neuropathic pain, two of the most difficult types of chronic pain to treat. More study in humans is needed in this area to substantiate the claims of CBD proponents about pain control.
Is cannabidiol safe?
Side effects of CBD include nausea, fatigue and irritability. CBD can increase the level in your blood of the blood thinner coumadin, and it can raise levels of certain other medications in your blood by the exact same mechanism that grapefruit juice does. A significant safety concern with CBD is that it is primarily marketed and sold as a supplement, not a medication. Currently, the FDA does not regulate the safety and purity of dietary supplements. So you cannot know for sure that the product you buy has active ingredients at the dose listed on the label. In addition, the product may contain other (unknown) elements. We also don’t know the most effective therapeutic dose of CBD for any particular medical condition. SEE: CBD Oil Drug Test
Is cannabidiol legal?
CBD is readily obtainable in most parts of the United States, though its exact legal status is in flux. All 50 states have laws legalizing CBD with varying degrees of restriction, and while the federal government still considers CBD in the same class as marijuana, it doesn’t habitually enforce against it. In December 2015, the FDA eased the regulatory requirements to allow researchers to conduct CBD trials. Currently, many people obtain CBD online without a medical cannabis license. The government’s position on CBD is confusing, and depends in part on whether the CBD comes from hemp or marijuana. The legality of CBD is expected to change, as there is currently bipartisan consensus in Congress to make the hemp crop legal which would, for all intents and purposes, make CBD difficult to prohibit. SEE: Does CBD Show Up On A Drug Test ?