Nospamin Drops

Nospamin drop is a medication containing homatroprine methylbromide (an anticholinergic) which is prescribed and used for infantile colic. Colic is when an infant who isn’t sick or hungry cries for more than 3 hours a day, more than 3 days a week, for more than 3 weeks. Nospamin is a peripherally acting anticholinergic medication that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous system. It does not cross the blood–brain barrier. When used correctly it can effectively relieve intestinal spasms and abdominal cramps, without producing the adverse effects of less specific anticholinergics.

Nospamin contains Homatropine Methyl bromide an antimuscarinic agent. Each 1ml contains Homatropine Methyl bromide USP 2mg. Evidence-based medicine has shown a clear benefit of this drug in the treatment of excessive crying in infants associated with stomach discomfort. Some experts believe that colic is the result of an allergy to cow’s milk proteins (or lactose intolerance) in formula-fed babies. Less often, colic may be a reaction to specific foods in Mom’s diet in breastfed babies. Either way, these allergies or sensitivity can cause tummy pain that may set off colicky behavior.


What is the dose of Nospamin drop for babies?

Dosage for infants – Doses should be according to body weight: 1mg per Kg body weight 3 – 4 times daily. Up to 3 months administer 2 – 4 drops, 3 to 4 times daily; 3 to 6 months, administer 4 – 6 drops, 3 to 4 times daily; 6 to 12 months, administer 6 to 9 drops, 3 to 4 times daily. Or follow the direction of your doctor. Infant doses are to be take 10 to 15 minutes before feeding.



Treatment with Nospamin in acute myocardial infection, thyrotoxicosis and cardiac insufficiency should be done with care. Not to be dispensed or repeated without medical prescription. If symptoms persist for more than two days consult your doctor. Do not use any medicine after the expiry date on the pack. Keep your medicine away from the reach of the children.


What is the side effect of Nospamin drop?

The following is a list of possible side-effects that may occur from all constituting ingredients of Nospamin Paediatric drops. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away:


  • Blurred vision
  • Burning
  • Eye itching
  • Urinary retention (rarely)


Nospamin Paediatric drops may also cause side-effects not listed here. If you notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority.


Can Adults Use Nospamin?

Yes. Available data suggests that the most effective safe dosage schedule of oral administration of homatropine methyl bromide in adults is 30 mg four times per day, the amount being decreased if unpleasant side-effects occur. The incidence of side-effects in patients receiving varying dosages over different periods of time varied directly with the size of the individual doses. Also Read: Does Abidec Drop Make Babies Gain Weight?


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